Cardiologist Flags 5 Drug Categories That May Affect Heart Health: What Patients Should Know
Kamal Singh|Newsdesk7
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New Delhi, September 17, 2026: Some medicines that are commonly used for pain, colds, attention disorders, diabetes and cancer treatment can have cardiovascular side effects in certain people, particularly when used at higher doses, for long periods or in people with existing heart conditions.
New Delhi, September 17, 2026: Some medicines that are commonly used for pain, colds, attention disorders, diabetes and cancer treatment can have cardiovascular side effects in certain people, particularly when used at higher doses, for long periods or in people with existing heart conditions.
A recent report quoting U.S. cardiologist Dr. Dimitry Yaranov highlighted five categories that deserve particular attention. However, these medicines are not inherently “bad” or unsafe for everyone, and patients should never stop a prescribed medicine without medical advice.
1. NSAID Painkillers
Common non-steroidal anti-inflammatory drugs (NSAIDs), including ibuprofen and naproxen, are widely used for headaches, muscle pain and inflammation.
Regular or prolonged use can cause fluid retention and increased blood pressure and may worsen heart failure in susceptible people. The risk is particularly important for people who already have cardiovascular or kidney problems.
What to do: If you need painkillers frequently, discuss the appropriate medicine and dose with your doctor rather than relying on regular self-medication.
2. Certain Cancer Treatments
Some chemotherapy and targeted cancer medicines can affect the heart. Drugs such as doxorubicin and trastuzumab are among treatments known to have potential cardiotoxic effects.
Because these medicines can be essential for treating cancer, doctors balance their benefits against cardiovascular risks and may monitor heart function during treatment.
Important: This does not mean cancer patients should discontinue treatment. Cardiology and oncology teams can work together to monitor and manage potential complications.
3. Stimulant Medicines
Certain stimulant medicines, including medications used for ADHD, can increase heart rate and blood pressure.
Research presented by the American College of Cardiology has also reported an association between long-term stimulant exposure and cardiomyopathy in young adults, although the absolute risk remained low.
People with existing cardiovascular problems should discuss their medical history and any symptoms with their doctor.
4. Some Older Diabetes Medicines
Certain older diabetes medicines, particularly the thiazolidinedione class, can cause fluid retention and may worsen or increase the risk of heart failure in susceptible patients. Rosiglitazone is one example that has been subject to cardiovascular safety concerns.
Modern diabetes treatment offers several alternatives, but the appropriate choice depends on a patient's blood sugar levels, kidney function, cardiovascular status and other factors.
Never change diabetes medication on your own.
5. Decongestants Used for Colds
Some cold and allergy medicines contain decongestants such as pseudoephedrine.
These medicines work partly by constricting blood vessels, which can raise blood pressure and increase cardiovascular stress. People with uncontrolled hypertension or certain heart conditions may need to avoid them or use them only after consulting a healthcare professional.
Does This Mean You Should Stop These Medicines?
No.
The important point is not that these medicines should automatically be avoided. Many are highly effective and, in some circumstances, life-saving.
The cardiovascular risk depends on factors such as:
Dose and duration of treatment Existing heart disease Blood pressure Kidney function Age and other health conditions Other medicines being taken simultaneously
Medical experts recommend reviewing medications regularly, particularly when someone takes several prescription and over-the-counter medicines.
Warning Signs That Should Not Be Ignored
Seek urgent medical attention for symptoms such as new or severe chest pain, significant breathlessness, fainting, a very rapid or irregular heartbeat, or sudden swelling of the legs.
These symptoms can have many causes, but they should not be dismissed as a normal medication side effect.
The Key Takeaway
The biggest message for patients is medication awareness, not medication fear. A medicine that carries cardiovascular risks for some patients may still be the appropriate treatment for another person.
Before starting, stopping or changing any prescription medicine, speak with your doctor or pharmacist and provide a complete list of the medicines and supplements you take.
